Welcome to POLITICO's West Wing Playbook, your guide to the people and power centers in the Biden administration. With help from Allie Bice. Send tips | Subscribe here | Email Alex JILL BIDEN has tried to make the president's proposed "Cancer Moonshot" initiative a centerpiece of her role as first lady. The country's partisan divisions have made the task difficult. In February, when the first lady visited the Moffitt Cancer Center in Tampa, her office invited Republican Gov. RON DESANTIS , a potential 2024 presidential rival, to attend. The center was where DeSantis' wife CASEY had recently been treated for breast cancer, an experience she has talked about on the campaign trail this fall . The governor declined, according to emails shared with West Wing Playbook. An official in DeSantis' office wrote back: "thank you for the invitation. Unfortunately, the Governor is unable to join." The first lady visited the center on Feb. 18 with Dr. NED SHARPLESS, the head of the National Cancer Institute . It was her second cancer-related event in the state. The first lady's office declined to comment. The first lady's interest in the cancer initiative is personal, owing in large part to the 2015 death of BEAU BIDEN. She and JOE BIDEN began their work a year later during the Obama administration and then launched the Biden Cancer Initiative in 2017. As president, Biden tried to reignite "Cancer Moonshot" in February but the new research agency at the center of the initiative, known as ARPA-H, received just a fraction of the initial funding sought by the administration, as we reported previously . In September, Biden signed an executive order to "break logjams" on funding and likened the task to going to the moon. The Bidens have also discovered that even something as unobjectionable as fighting cancer has not been immune from politics in 2022. Last month, when the first lady attended a cancer awareness night at the Philadelphia Eagles' stadium in her hometown, some fans booed her and shouted, "Let's go Brandon" ( viral clips with fake audio exaggerated the heckles ). A few people in Biden world told West Wing Playbook they are bracing for the first lady to get booed again Wednesday night when she returns to Philly for Game 4 of the World Series as part of a cancer awareness initiative with MLB. The first lady has shown no reluctance to bring her message into tough environs. She recently sat for an extended interview with Newsmax. The talk focused on her cancer advocacy, was substantive, and helped her reach a more conservative audience. But the efforts to reach across the aisle have not resulted in an entirely de-politicized reception. And the ups-and-downs over the current cancer initiative have become emblematic of the sharp partisanship that has occasionally caught both Bidens off-guard. They have tried to recently engage in the sort of partisan barbs that don't always come naturally. On Tuesday night at a fundraiser, Biden called DeSantis "Donald Trump incarnate." MESSAGE US — Are you RON DESANTIS? We want to hear from you! Seriously! And we'll keep you anonymous! Email us at westwingtips@politico.com .
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