What if revolutionizing cancer treatment starts in the operating room? That’s a question Dr. Ileana Hancu, program manager at the Advanced Research Projects Agency for Health — the new agency tasked with funding high-risk, high-reward research — is seeking to answer. Her program, Precision Surgical Interventions, put out a call last month for research proposals to dramatically improve surgery. “Surgery is the first avenue for treating cancer,” Hancu told Erin. “If it’s detected relatively early and you manage to take it out entirely, oftentimes that’s it — that person may be cured,” she said. “We tend to invest a lot of money in drugs, and obviously, there is a place for drugs, but if we significantly improve surgery that can go a long way toward treating this problem.” The field itself may also be ripe for innovation. Surgeons often tell Hancu that their tools haven’t changed over the last 50 years. Female surgeons have even developed hand problems because their tools, designed for men, are too big, she said. Hancu envisioned a few potential avenues for innovation: — Bedside devices. A surgeon removes patient tissue and places it on a bedside device, which scans the tissue for cancer cells. Instead of waiting for lab results, the surgeon knows immediately whether to remove more cells or close up the patient. — Inside-the-body imaging. Direct imaging of the inside of the patient’s body during laparoscopic surgery, which is performed through small incisions, could allow surgeons to remove cancer cells left behind during the initial procedure. — Smart surgical tools. A scalpel or electrocautery tool could have a warning light to indicate when surgeons approach a nerve to prevent doctors from accidentally injuring patients. Why it matters: Nearly two million Americans are diagnosed with cancer each year, according to the American Cancer Society. Accidentally damaging healthy tissue can mean more operations, pain and extended hospital stays. Those corrective procedures and treatments cost the U.S. more than $1 billion each year. What's next? “We’re hopeful that in a timespan of five to seven years, the tools that we develop will be in ORs across the countries. We’re not developing esoteric projects that are going to put out nice papers in Nature,” Hancu said. “What we’re really going for is a difference in how health care is done.” For interested researchers in fields like oncology, surgery and imaging technology, Proposer’s Day is Sept. 7. |
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