The health tech revolution assessed

The ideas and innovators shaping health care

Feb 23, 2024 View in browser   By Gregory Svirnovskiy, Erin Schumaker, Daniel Payne, Carmen Paun and Ruth Reader FOLLOW THE MONEY Telemedicine took off during the Covid pandemic. | LM Otero/AP Photo Some of the country’s most prominent health care organizations are launching a coalition dedicated to advancing digital health. The Digital Health Collaborative will conduct a national purchasing survey, create grants and hold events to bring thought leaders together. Who’s in? The lobby for older adults, AARP; the American Medical Association; the Consumer Technology Association; the American Telemedicine Association; and AHIP, the lobby for insurance companies, and nine others. What’s up? The collaborative awarded its first grant to the Digital Medicine Society, a professional group for people who work in health tech, funding a project to help square health tech innovations with FDA regulatory requirements. What they’re saying: “The Digital Health Collaborative is raising the bar for guidance, research and resources that can accelerate the adoption of solutions that work and are worth it,” Meg Barron, a managing director at the Peterson Health Technology Institute, a nonprofit supporting the coalition, said in a press release. Vantage point: Venture capital funding for digital health companies plummeted in 2023, according to a Rock Health report, with just $10.7 billion raised across 492 deals. It’s a long way from the sector’s most recent heyday, when the shift to online medicine prompted by Covid-19 led to an investment of $29 billion in almost 750 deals in 2021.   CONGRESS OVERDRIVE: Since day one, POLITICO has been laser-focused on Capitol Hill, serving up the juiciest Congress coverage. Now, we’re upping our game to ensure you’re up to speed and in the know on every tasty morsel and newsy nugget from inside the Capitol Dome, around the clock. Wake up, read Playbook AM, get up to speed at midday with our Playbook PM halftime report, and fuel your nightly conversations with Inside Congress in the evening. Plus, never miss a beat with buzzy, real-time updates throughout the day via our Inside Congress Live feature. Learn more and subscribe here.     WELCOME TO FUTURE PULSE Hull, Mass. | Shawn Zeller/POLITICO This is where we explore the ideas and innovators shaping health care. Scientists think they may have cracked the mystery of how whales sing: a specialized voice box not seen in other animals, AP reports. Share any thoughts, news, tips and feedback with Carmen Paun at cpaun@politico.com, Daniel Payne at dpayne@politico.com, Ruth Reader at rreader@politico.com or Erin Schumaker at eschumaker@politico.com. Send tips securely through SecureDrop, Signal, Telegram or WhatsApp.   THE LAB AI could help prevent drug interactions, researchers believe. | Getty Artificial intelligence that can identify drugs which shouldn’t be taken together could improve the effectiveness and safety of care. Researchers from the Massachusetts Institute of Technology, Brigham and Women’s Hospital, and Duke University have built a machine-learning model that aims to do that. Why it matters: After a drug is taken orally, it passes through the digestive tract lining with the help of transporter proteins. But scientists don’t know which transporter proteins different drugs use to pass through the lining. If two drugs use the same transporter, they could interfere with one another. How so? The researchers built a model to measure how intestinal tissue absorbed certain commonly used drugs. They then trained a machine-learning algorithm based on their new data and existing drug databases, teaching the new algorithm to predict which drugs would interact with which transporter proteins. They analyzed 28 commonly used and 1,595 experimental drugs using that new model, which predicted nearly 2 million potential drug interactions. When they tested the predictions against patient data, they confirmed one prediction about an antibiotic interacting with other drugs. “These are drugs that are commonly used, and we are the first to predict this interaction using this accelerated in silico and in vitro model,” the study’s senior author, Giovanni Traverso, said in a statement. “This kind of approach gives you the ability to understand the potential safety implications of giving these drugs together.” What's next? In addition to checking for existing drug interactions, the researchers hope their model could one day help drug developers tweak their formulas to prevent interactions. The National Institutes of Health-backed study was published in the journal Nature Biomedical Engineering this week.   YOUR TICKET INSIDE THE GOLDEN STATE POLITICAL ARENA: California Playbook delivers the latest intel, buzzy scoops and exclusive coverage from Sacramento and Los Angeles to Silicon Valley and across the state. Don't miss out on the daily must-read for political aficionados and professionals with an outsized interest in California politics, policy and power. Subscribe today.     AROUND THE NATION Wider electric car adoption could bring health benefits, a study says. | Scott Olson/Getty Images A “widespread transition” to electric vehicles would reduce air pollution and cut the number of pediatric respiratory issues, according to a new report from the American Lung Association. How so? For kids in the U.S., the report predicts a move to zero-emission vehicles could mean: — 2.79 million fewer asthma attacks — 147,000 fewer acute bronchitis cases — 2.67 million fewer upper-respiratory symptoms — 508 fewer infant mortality cases Children are disproportionately affected by air pollution, the report says, because their bodies are still developing and they’re typically exposed to more outdoor air than adults. Nearly 27 million kids live in places affected by unhealthy air quality, the group says. Even so: To achieve the forecasted gains, the analysis suggests taking aggressive action over the next 10 to 15 years, including only selling new passenger vehicles with zero emissions and shifting to a noncombustion electric grid by 2035. The group called for the EPA to roll out stronger rules limiting the pollution allowed from vehicles and government officials to push for a faster transition to electric vehicles.   Follow us on Twitter Carmen Paun @carmenpaun Daniel Payne @_daniel_payne Ruth Reader @RuthReader Erin Schumaker @erinlschumaker   Follow us

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